Members of the working group:
- Claire Edwards
- Gina Woods
- Dimitrios Karampinos
- Olaia Naveiras
- Annegreet Veldhuis-Vlug
- Greet Kerckhofs
- Nathalie Bravenboer
- Biagio Palmisano
- Antonella Poloni
- Francoise Pflumio
- Jeanine Prompers
- Eleni Douni
- Izabela Podgorski
- Kaiyan Liu
- Josefine Tratwal
- Sammy Badr
- Parastoo Boroumand
- Maria Jesús Moreno Aliaga
- Clifford Rosen
- Sarah Beck-Cormier
- Rossella Labella
- Eleni Douni
- Shanti Rojas-Sutterlin
Aim(s):
Establish use of standardized methodologies related to the assessment of BMA
Approach:
The working group will identify currently used methodologies related to BMA. These will be discussed with the aim to come up with standardized protocols after which the working group writes a draft file, including the proposed methodologies that will be sent around to the BMAS EB, SB and GA members for additional feedback. If approved, the draft file can be finalized and published to guarantee future use of these methodologies globally.
Issues related to methodologies:
- Methodologies to consider for discussion include cell culture, analysis methods, such as osmium staining, Marrow Quant, MRI etc.
- Identify subject-related factors in the methodologies that may explain inter-laboratory variation (age, sex, strain, etc.)
- Identify environment-related factors in the methodologies that may explain inter-laboratory variation (temperature, humidity, commonly used chemicals/compounds, etc.)
Update: Methodologies paper is now published!
