Deputy Director of the Lab Pathophysiology of Inflammatory Bone diseases, with expertise in the study of bone marrow adipocytes in mouse models of chronic energy deficit, and bone marrow stem cell (BMSC) differentiation. Member of the executive board of the French Society for Biology of Mineralized Tissues, and member of the Scientific Board of BMAS. Current research focuses on the regulation of BMA and BMSC differentiation in several mouse models displaying bone loss.
Principal investigator at the Technical University of Munich with expertise on Magnetic Resonance Imaging. Member and Junior Fellow of the International Society of Magnetic Resonance in Medicine. Current research focuses on the development of quantitative magnetic resonance imaging biomarkers of adipose tissue and musculoskeletal tissues (bone marrow, bone, skeletal muscle, peripheral nerves). Further details can be found here (http://bmrrgroup.de/)
Principal investigator in the Division of Bone and Mineral Diseases at Washington University in Saint Louis, with expertise in bone biology, endocrine physiology, neurobiology, and oral health science. Member of ASBMR and BMAS and review editor for Frontiers in Endocrinology. Current research focuses on identifying mechanisms underlying neural regulation of marrow adipose tissue biology and defining the relationship between neuropathy and skeletal disease. Further details can be found here (www.marrowad.com).
Clinical fellow in Endocrinology specializing in metabolic bone diseases at the Academic Medical Center in Amsterdam and the Erasmus Medical Center in Rotterdam, the Netherlands. Postdoctoral researcher in the Rosen Musculoskeletal Laboratory Maine Medical Center Research Institute, Scarborough, USA. Member of the Dutch Calcium and Bone Metabolism Society, European Calcified Tissue Society (ECTS), American Society for Bone and Mineral Research (ASBMR), Dutch Endocrine Society and European Society for Endocrinology (ESE), and the Endocrine Society. Member of the ECTS Academy and International Endocrine Scholar of the ESE. Current research focuses on the endocrine regulation of human bone marrow adiposity, with experience in clinical trials using MRI, histomorphometry and cell culture to assess bone marrow adiposity.
Director of the Basic Science Laboratories in the Department of Medicine, Stellenbosch University. Our research focuses on the biology of mesenchymal stem cells (MSCs) from fat and bone. Current projects encompass examining the fine balance between adipogenesis and osteoblastogenesis in different subpopulations of MSCs in bone, the effects of obesity and diabetes on wound healing and the modulation of adipogenesis by endocrine factors.
Principal investigator at the Institute of Mechanics, Materials and Civil Engineering of the UCLouvain (Belgium), running the Biomechanics lab. Expertise in quantitative contrast-enhanced X-ray microfocus computed tomography imaging (CE-CT) for virtual 3D anatomical pathology of biological tissues, mechanical testing of biological tissues and tissue engineering. Member of the scientific board of Prometheus (KU Leuven, Belgium) and 10% Visiting Professor at the Dept. Materials Engineering (KU Leuven, Belgium).
Current research aims to provide a better understanding of the relationship between structure, function and biological performance of biological systems, such as humans, animals, organs, tissues, cells. Particularly, strong expertise in 3D imaging, and more specifically CE-CT, which enables to visualize and structurally analyze in 3D multiple biological tissues (both mineralized and soft).
Further detail can be found here (https://uclouvain.be/en/research-institutes/immc/meed/biomechanics.html).
Principal investigator in the Center for Molecular Medicine at the Maine Medical Center Research Institute in Scarborough, Maine. Expertise in preclinical studies of multiple myeloma, cancer-induced bone disease, bone marrow adipocytes, tissue engineering, and osteocyte/adipocyte crosstalk. Member of ASBMR, ASH, and BMAS, a Board member of AIMM, and Chair of the Committee of Women in Bone and Mineral Research in the ASBMR. Current research focuses on identifying mechanisms underlying marrow adipose effects on and responses to multiple myeloma cancer cells, and defining the relationship between marrow adipocytes and other cells in the bone, such as osteocytes and osteoblasts. Further details can be found here (http://mmcri.org/ns/?page_id=5832).
Our laboratory studies the mechanisms that regulate stem cell self-renewal and the ways by which such mechanisms get hijacked by cancer. Our laboratory has two major research focuses:
1. The cellular identity of hematopoietic stem cell niche. Our research interest is to elucidate the exact cellular identity of HSC niche in vivo and to reconstruct it in vitro.
2. The physiological functions of mesenchymal stem cells. Our research interest is to investigate to what extent endogenous MSCs contribute to tissue repair and regeneration in different organs.